Share benchmarks have closed on a lower note on Wednesday, amid investors keenly awaited for cues from US Fed meeting that ends later today. The BSE Sensex fell 109.79 points to 36,542.27 while the Nifty50 index fell 13.70 points to 11,053.80. Indiabulls Housing Finance, UPL, Vedanta, Titan, Hindalco were among major gainers on the NSE, while Tata Motors, SBI, Bharti Infrael, ITC and Wipro were top losers.